Faculty of Science

Annual Review 2017

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Pamela Ohashi (York BSc Hons 1982) was inspired early in her academic career to pursue research in the ght against cancer after witnessing her grandmother's dif cult battle with the disease. Now, she is developing new therapies against cancer at the Princess Margaret Cancer Centre as a senior scientist, co-director of the Campbell Family Institute for Breast Cancer Research and director of the Tumor Immunotherapy Program. She is also a Canada Research Chair in Tumor Immunity and Immunotherapy (Tier 1) at the University of Toronto. Her rewarding career in biomedical research was launched from the platform of a BSc from York University. At York, Ohashi had the opportunity to work in several biology labs as a summer research student. She then pursued research in immunology, which at that time was undergoing rapid transformation due to the recent discovery of the T cell antigen receptor. Working in this new area, she received her PhD from the University of Toronto and completed post-doctoral training with Nobel Laureate Rolf Zinkernagel at the University of Zurich. Her current work is focused on understanding how to manipulate and improve the function of cytotoxic T cells of the immune system, with the goal to design new treatments that enhance immune responses against cancer. T cells are a population of white blood cells that protect our bodies against infection, but they also have the potential to protect us against tumour cell growth. Ohashi's research team was among the rst to deliver T cell immunotherapy to cancer patients in Canada. York University is proud to count Pamela Ohashi among its Science graduates. She is pursuing a lifelong dream and making outstanding contributions to science and medicine, ith the potential to impact millions of cancer patients in the years to come. lumni spotlights: Pamela Oha hi 3 8 YO RK U NIVERSIT Y FACU LT Y O F SCIEN CE N OtablE alu m Ni

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